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Shin Nippon Biomedical Laboratories, Ltd. Translational Research Business

Japanese

A Leading Company in Nasal Drug Delivery

Nasal Drug Delivery

SNBL’s nasal drug delivery platform is a proprietary system consisting of powder carrier technology and delivery device technology.

Widely Applicable Technology

For Absorption
For Vaccination
For Nose-to-Brain

Expertise in Nasal Delivery

3D Nasal Cast Model

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Platform Technology

Proprietary Nasal Drug Delivery System

SNBL has developed a proprietary nasal drug delivery technology, μco™ System, consisting of a powder carrier technology (μco™ Carrier) designed for increased drug absorption through its muco-adhesive properties and a delivery device technology designed for simple use, and complete and consistent delivery of intranasal powder formulations.
Our technology can be applied to a wide range of drugs, including small molecules, peptides, and biologics. It can be utilized for improved systemic drug absorption, enhanced muco-immunity for a vaccine, or for enabling drug delivery to the brain through the olfactory area.

Platform Technology

The μco™ System is a nasal drug delivery platform comprised of powder carrier technology and delivery device technology.

Powder Formulation Technology
μco™ Carrier

  • Powder carrier
  • Use of safety-proven pharmaceutical additives (FDA GRAS*)
  • Excellent safety profile in clinical trials in more than 150 subjects
  • Compatibility with the mucosal membrane
  • Muco-adhesive
  • Versatility of application to a wide range of drugs
  • Increased stability of formulation at room temperature

*GRAS: Generally Recognized as Safe: The U.S. Food and Drug Administration (FDA) designation that a chemical or substance added to food is generally recognized to be safe.

Delivery Device Technology
Fit-lizer™

  • Complete and consistent delivery
  • Light-weight and compact
  • User-friendly
  • Designed for safe use
  • Biocompatible (ISO-10993)
  • Developed by reference to US regulations for combination products (21CFR Part 4 and 820)
A new nasal delivery device is currently under development.

Special Analyses for Nasal Drug Delivery System

Special analyses for the development of our nasal drug delivery technology

  • Primary particle size
  • Secondary particle size
  • Aerodynamic particle size
  • Plume geometry
  • Spray pattern
  • Nasal delivery devices for animal
  • Distribution analysis with human nasal cavity cast model
  • Distribution analysis with non-human primate nasal cavity model

Publication

ONdrugDelivery Magazine

( www.ondrugdelivery.com )

Drug Development and Delivery Magazine

( www.drugdeliverytech.com )